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ob0002p8 | (1) | OU2020

Proglucagon peptide secretion post Roux-en-Y gastric bypass: one year prospective study

Alexiadou Kleopatra , Cuenco Joyceline , Howard James , Albrechtsen Nicolai Wewer , Ilesanmi Ibeyimi , Kamocka Anna , Tharakan George , Behary Preeshila , Ahmed Ahmed R , Holst Jens J , Bloom Stephen R , Khoo Bernard , Tan Tricia M

Background: Hyperglucagonaemia is one of the key players in the pathophysiology of type 2 diabetes. Roux-en-Y Gastric Bypass (RYGB) is currently a highly effective treatment for weight loss and diabetes remission. However, the role of glucagon in the above effects is unclear.Aim: To characterise the behaviour of proglucagon-derived peptides (glucagon, glucagon-like peptide-1, oxyntomodulin, glicentin) after RYGB surgery.Subjects an...

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ob0003cd2.2 | Case Discussions 2 | OU2021

Glycaemic variability assessed by continuous glucose monitoring after Roux-en-Y gastric bypass vs. sleeve gastrectomy

Alexiadou Kleopatra , Malallah Khalefah , Ilesanmi Ibiyemi , Tabbakh Yasmin , Kenkre Julia , Choudhury Sirazum , Behary Preeshila , Tharakan George , Purkayastha Sanjay , Tsironis Christos , Hakky Sherif , Ahmed Ahmed R , Bloom Stephen R , Tan Tricia M

Background: Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy are two widely used bariatric procedures. Longitudinal data have shown similar efficacy in terms of sustained weight loss and diabetes remission in obese patients with type 2 diabetes. Altered glucose dynamics with increased glycaemic variability and the occurrence of hypoglycaemia are common post-bariatric surgery. Aim: To compare the glycaemic variability and incidence of hypoglycaemia ...

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Obesity Abstracts

Proglucagon peptide secretion post Roux-en-Y gastric bypass: one year prospective study

Glycaemic variability assessed by continuous glucose monitoring after Roux-en-Y gastric bypass vs. sleeve gastrectomy

BiosciAbstracts